Evolución y comprensión de la espondiloartritis axial
DOI:
https://doi.org/10.47464/MetroCiencia/vol34/2/2026/89-91Keywords:
axial spondyloarthritis, Chronic lower back pain, BiomarkersAbstract
Dear Editor:
I am writing to comment on the evolution of the concept of axial spondyloarthritis (axSpA) in the context of chronic low back pain, and how this interrelationship is redefining the diagnosis and treatment of patients. I found the published paper, "The Journey from Chronic Low Back Pain to the Diagnosis of Spondyloarthritis," very enlightening (1).
Building upon the published article, I am pleased to share and complement the review presented by the authors, highlighting the importance of their work. My aim is for both medical trainees and academics to continue strengthening this topic in their studies and practices (1,2).
The analyzed texts indicate a significant shift in the understanding and classification of axSpA. Traditionally, this condition was defined by the presence of erosions in the sacroiliac joints, according to the New York criteria. However, advancements in imaging techniques, such as magnetic resonance imaging (MRI), along with research in genetics and biomarkers, have broadened this conception to include non-radiographic forms. This shift is crucial, as chronic low back pain often represents the first symptom prompting patients to seek medical attention (1,3).
It is emphasized that, although there is considerable consensus within the scientific community regarding the nature of axSpA, disagreements persist regarding certain classification criteria. The lack of specificity in current diagnostic definitions, particularly concerning MRI findings, underscores the complexity of differentiating between various etiologies of low back pain. This is critical, as inflammatory low back pain may result from conditions such as spondyloarthritis, and early identification can significantly alter patient prognosis (1,2,4).
Additionally, the analysis provides essential clinical context by detailing the origins and characteristics of pain. The importance of identifying accompanying symptoms that may indicate the presence of spondyloarthritis, such as pain that improves with physical activity and morning stiffness, is highlighted. This underscores the need for a comprehensive evaluation that considers not only the mechanical aspects but also the inflammatory components of low back pain (1,2,4).
In conclusion, it is imperative for clinicians to stay informed about these advancements to optimize the diagnosis and treatment of patients with chronic low back pain. Ongoing research and the development of new classifications are vital to addressing current discrepancies and improving patient care (2,4). See Tables No. 1 to 3.
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References
Mestanza-Peralta M; Uguña-Sari F. El camino desde el dolor lumbar crónico hasta el diagnóstico de la espondiloartritis. MetroCiencia [Internet]. 31 de marzo de 2023; 31(1):51-59. Disponible en: https://doi.org/10.47464/MetroCiencia/vol31/1/2023/51-59
Robinson, P.C., van der Linden, S., Khan, M.A. et al. Axial spondyloarthritis: concept, construct, classification and implications for therapy. Nat Rev Rheumatol 17, 109–118 (2021). https://doi.org/10.1038/s41584-020-00552-4
Danve, A., Deodhar, A. Treatment of axial spondyloarthritis: an update. Nat Rev Rheumatol 18, 205–216 (2022). https://doi.org/10.1038/s41584-022-00761-z
Cozzi, G., Scagnellato, L., Lorenzin, M. et al. Spondyloarthritis with inflammatory bowel disease: the latest on biologic and targeted therapies. Nat Rev Rheumatol 19, 503–518 (2023). https://doi.org/10.1038/s41584-023-00984-8
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Copyright (c) 2026 Jhan Sebastian Saavedra Torres

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